Approximately 10km after Alessandria take the road from Gamalero to Mombaruzzo and enjoy stunning view of the UNESCO protected landscape of the Monferrato.
After Mombaruzzo continue to Casalotto and then eventually to Castel Boglione for an intimate view of the Piemontese countryside.
After Castel Boglione follow for Terzo and finally Bistagno.
When you arrive in Bistagno on road SS30 take the exit to the right and cross the railway lines. Continue through Bistagno and follow road SP25 towards Monastero Bormida.
After approximately 5 minutes you will pass a sign on your right side that says Sessame – you are now very close to Villa La Madonna!
Continue for approximately 200 meters over a bridge and then take the first right onto a very small gravel road with a sign that says Regione Madonna. Continue past the farm and soon you will see Villa La Madonna on your right!